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A case report of spontaneous pregnancy during hormonal replacement therapy for premature ovarian failure

Author(s): Firoozeh Akbari Asbagh | Mahbod Ebrahimi

Journal: Iranian Journal of Reproductive Medicine
ISSN 1680-6433

Volume: 9;
Issue: 1;
Start page: 47;
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Keywords: Premature ovarian failure | Transient ovarian failure | Hypergonadotropic hypogonadism | Hypergonadotropic amenorrhea | Hormone replacement.

Background: Premature ovarian failure (POF) is a common condition; its incidence is estimated to be as great as 1 in 100 by the age of 40 years. Physiologic replacement of ovarian steroid hormones seems rational until the age of normal menopause. Temporary return of ovarian function and pregnancy may occur rarely in women with POF. We report a case of POF who conceived during hormone replacement therapy.Case: A 30 years-old woman with confirmed POF after pelvic surgery and sever emotional stress conceived spontaneously.Conclusion: Return of ovarian function and achievement of pregnancy is possible in women with POF.
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