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Causes of hospitalization in children with infectiousmononucleosis --- Przyczyny hospitalizacji dzieci z mononukleozs zakasns

Author(s): Ewa Talarek | Ewa Duszczyk | Jolanta Popielska | Sabina Dobosz | Barbara Kowalik-Mikolajewska | Malgorzata Aniszewska

Journal: Przegląd Pediatryczny
ISSN 0137-723X

Volume: 37;
Issue: 2;
Start page: 217;
Date: 2007;
Original page

Introduction: Infectious mononucleosis is a self-limiting disease with good prognosis. However, some patients require hospitalization. The aim of the study was analysis of causes of hospitalization in children with infectious mononucleosis. Material and methods: In 2004-2006 218 children (119 boys and 99 girls) with infectious mononucleosis were hospitalized. The age ranged from 10 months to 16.5 years. In all cases diagnosis of infectious mononucleosis was confirmed by presence of hete-rophil or/and specific antibodies anti-VCA IgM. Results: 55% of children were younger than 6 years. In 129 (59.2%) children the cause of hospitalization was upper airway obstruction which required steroids. In 100 (45.6%) children secondary bacterial infection was diagnosed (pharyngitis, acute otitis, pneumonia, bronchitis, scarlet fever, lymphadenitis). In 72 (33%) children both upper airway obstruction and bacterial pharyngitis were diagnosed. 54 (24.7%) children were admitted to the hospital because of intensive allergic rash after treatment with amoxicillin (44) or other antibiotics (10). In one child Gianotti-Crosti syndrome was diagnosed. In 23 (10.5%) children hepatitis occurred with ALT activity >200 U/l, among them in 4 cases antibodies anti-HAV IgM were detected, in one - coinfection with EBV and CMV was diagnosed (with acute liver failure) and in one - liver damage by isoniasid. Four children were admitted because of diarrhorea. Conclusions: The most common causes of hospitalization of children with infectious mononucleosis were upper airway obstruction and secondary bacterial infection.
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