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Celiac disease: Association with adult-onset Still′s disease: Apropos of a clinical case

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Author(s): Kumar Sachin | Gupta N | Jhamb Rajat | Mishra Deepak

Journal: Indian Journal of Medical Sciences
ISSN 0019-5359

Volume: 61;
Issue: 7;
Start page: 414;
Date: 2007;
Original page

Keywords: Adult-onset Still′s disease | autoimmune diseases | methotrexate

ABSTRACT
Adult-onset Still′s disease (AOSD) is a rheumatic disorder of unknown etiology characterized by a triad of fever, polyarthritis and evanescent rash. We present a case report of a 28-year-old female who presented with complaints of fever, joint pains, rash, weakness for the past 4 years and diarrhea for the past 2 years. On investigation the patient was diagnosed to be a case of AOSD. Duodenal biopsy report was suggestive of celiac disease with a positive IgA tissue transglutaminase and anti-endomysial antibody. The patient was started on weekly methotrexate and gluten-free diet, and her symptoms gradually improved. The patient remains in our follow-up and is doing well.

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