Author(s): Stevo Najman | Ljubiša Đorđević | Vojin Savić | Nenad Ignjatović | Miroslav Miljković | Perica Vasiljević | Dragan Uskoković
Journal: Acta Medica Medianae
ISSN 0365-4478
Volume: 44;
Issue: 3;
Start page: 5;
Date: 2005;
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Keywords: SEM | polysiloxane/hydroxyapatite | implant | peritoneum
ABSTRACT
Siloxane polimers have been widely used in biomedicine and pharmacy due to their biocompatibility. Hydroxyapatite (HAp) is a natural constituent of bones, and therefore widely used in maxillofacial and orthopedic surgery. HAp itself is amorphous and without elasticity, so its characteristics can be improved when combined with organic polymers. We evaluated the interaction of cells and composites made of polydimethylsiloxane (PDMS) and HAp by scanning electron microscopy (SEM) 10 days after their intraperitoneal implantation into Balb/c mice. Two composites which were different in the quantity of HAp were analyzed. Both of them showed high adhesive characteristics for different cell types. The erythrocytes in cell clusters could be seen on the surface of the composite with higher quantity of HAp.
Journal: Acta Medica Medianae
ISSN 0365-4478
Volume: 44;
Issue: 3;
Start page: 5;
Date: 2005;
VIEW PDF
DOWNLOAD PDF Original pageKeywords: SEM | polysiloxane/hydroxyapatite | implant | peritoneum
ABSTRACT
Siloxane polimers have been widely used in biomedicine and pharmacy due to their biocompatibility. Hydroxyapatite (HAp) is a natural constituent of bones, and therefore widely used in maxillofacial and orthopedic surgery. HAp itself is amorphous and without elasticity, so its characteristics can be improved when combined with organic polymers. We evaluated the interaction of cells and composites made of polydimethylsiloxane (PDMS) and HAp by scanning electron microscopy (SEM) 10 days after their intraperitoneal implantation into Balb/c mice. Two composites which were different in the quantity of HAp were analyzed. Both of them showed high adhesive characteristics for different cell types. The erythrocytes in cell clusters could be seen on the surface of the composite with higher quantity of HAp.
