Author(s): R.D. Langer | K. Neidl van Gorkom | P. Raupp
Journal: Iranian Journal of Radiology
ISSN 1735-1065
Volume: 5;
Issue: 1;
Start page: 25;
Date: 2008;
Original page
Keywords: tuberous sclerosis
ABSTRACT
Tuberous sclerosis (TS) is a developmental neuroectodermal disorder, affecting multiple organ systems. Most patients are diagnosed at the age of five years or later. Only recently, mutation analysis of TS Complex genes has enabled us make an early or even an antenatal diagnosis of the disease. Early onset with infantile seizures is mainly an ominous sign for an unfavorable outcome."nMRI findings in older children and adults are well-known; however, only limited publications illustrate brain MRI findings in newborns. "nWe present a female neonate with a positive family history, categorized as "definite TS." On MRI of the brain, white matter lesions were depicted. MRI findings were correlated with published data on neonatal TS.
Journal: Iranian Journal of Radiology
ISSN 1735-1065
Volume: 5;
Issue: 1;
Start page: 25;
Date: 2008;
Original page
Keywords: tuberous sclerosis
ABSTRACT
Tuberous sclerosis (TS) is a developmental neuroectodermal disorder, affecting multiple organ systems. Most patients are diagnosed at the age of five years or later. Only recently, mutation analysis of TS Complex genes has enabled us make an early or even an antenatal diagnosis of the disease. Early onset with infantile seizures is mainly an ominous sign for an unfavorable outcome."nMRI findings in older children and adults are well-known; however, only limited publications illustrate brain MRI findings in newborns. "nWe present a female neonate with a positive family history, categorized as "definite TS." On MRI of the brain, white matter lesions were depicted. MRI findings were correlated with published data on neonatal TS.
