Academic Journals Database
Disseminating quality controlled scientific knowledge

Chemical Composition and Aminoglycosides Synergistic Effect of Lantana montevidensis Briq. (Verbenaceae) Essential Oil

Author(s): Erlânio O. Sousa | Fabiola F. G. Rodrigues | Henrique D. M. Coutinho | Adriana R. Campos | Sidney G. Lima | José Galberto M. Costa

Journal: Records of Natural Products
ISSN 1307-6167

Volume: 5;
Issue: 1;
Start page: 60;
Date: 2011;
VIEW PDF   PDF DOWNLOAD PDF   Download PDF Original page

Keywords: Lantana montevidensis | chemical composition | antibacterial and modulatory activities.

The leaves of Lantana montevidensis Briq. (Verbenaceae) were subjected to hydrodistillation, and the essential oil extracted was examined with respect to chemical composition, antibacterial and antibiotic modifying activity by gaseous contact. Among the 19 identified components, β- caryophyllene (31.50%) , germacrene D (27.50%) and bicyclogermacrene (13.93%) were the main constituents. The essential oil volatile constituents inhibited the growth of Staphylococcus aureus and Pseudomonas aeruginosa with a MID o 0.25 and > 1 mg/L, respectively. The activity of the antibiotics gentamicin and amikacin was reinforced against S. aureus and P. aeruginosa (with a 102% of amikacin activity against P. aeruginosa) after contact with the volatile components, showing that this oil influences the activity of the antibiotic and may be used as an adjuvant in the antibiotic therapy of respiratory tract bacterial pathogens.

Tango Jona
Tangokurs Rapperswil-Jona

     Affiliate Program