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Chemical Constituents and Antioxidant Activity of Geranium wallichianum

Author(s): Mohammad Ismail | Mohammad Ibrar | Zafar Iqbal | Javid Hussain | Hidayat Hussain | Manzoor Ahmed | Asma Ejaz | Muhammad I. Choudhary

Journal: Records of Natural Products
ISSN 1307-6167

Volume: 3;
Issue: 4;
Start page: 193;
Date: 2009;
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Keywords: Geranium wallichianum | antioxidant activity | DPPH | coumarin | triterpenoid | steroid.

The study of the chemical constituents of the whole plant of Geranium wallichianum (Geraniaceae) has resulted in the isolation and characterization of six compounds. These six compounds were identified as ursolic acid (1), β-sitosterol (2), stigmasterol (3),b-sitosterol galactoside (4), herniarin (5), and 2,4,6-trihydroxyethylbenzoate (6) which were isolated for the first time from Geranium wallichianum. The above compounds were individually identified by spectroscopic analyses and comparisons with reported data. The antioxidant potential of Geranium wallichianum extracts has been investigated by DPPH radical scavenging assay and EtOAc extract was found to be most potent with IC50 19.05 ug/mL
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