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The Chicken GGA-Mir-1658* Gene: Seed Region Polymorphisms, Frequency Distribution and Putative Targets

Author(s): Li-Ying Geng | Chuan-Sheng Zhang | Yang-Yang Li | Ya-Ya Li | Qiu-Yuewang | Hong-Nuan Sun | Xiao-Song Li

Journal: Journal of Animal and Veterinary Advances
ISSN 1680-5593

Volume: 10;
Issue: 9;
Start page: 1187;
Date: 2011;
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Keywords: Gga-mir-1658* | chicken | SNP | breeding | annotation | China

The aim of this study was to investigate the rs16681031 SNP located in seed regions of chicken gga-mir-1658* gene with PCR-RFLP using PvuII nuclease in 6 chicken populations 180 individuals. The finding represents that genotype frequencies of the gga-mir-1658* gene C>G has significant differences in Beijing Fatty and other chicken breeds. Bioinformatics analyses indicated that gga-mir-1658* gene C>G polymorphism may alter target selection and secondary structure. The findings indicate that the rs16681031 SNP may exert profound biological effects in the formation of some special phenotype of chicken and enables functional annotation of gga-mir-1658* gene.
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