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Childhood Intracranial Germinoma with Granulomatous Reaction

Author(s): Gülen GÜLNİFLİOĞLU | Mehtat ÜNLÜ | Nurullah YÜCEER | Erdener ÖZER

Journal: Türk Patoloji Dergisi
ISSN 1018-5615

Volume: 27;
Issue: 1;
Start page: 87;
Date: 2011;
Original page

Keywords: Brain | Germ cell neoplasms | Germinoma | Granuloma | Corpus callosum

Central nervous system tumors are the second most common type of childhood cancer in Turkey. Germinomas constitute two thirds of intracranial germ cell tumors. The granulomatous inflammation occurring around germinomas can cause histological diagnostic difficulty. We present a 12-year-old girl with a diagnosis of germinoma in the corpus callosum associated with granulomatous reaction to emphasize the diagnostic challenge which may occur during stereotactic biopsy interpretation or intraoperative consultation.

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