Author(s): David L Porter, Michael Kalos, Zhaohui Zheng, Bruce Levine, Carl June
Journal: Journal of Cancer
ISSN 1837-9664
Volume: 2;
Issue: 1;
Start page: 331;
Date: 2011;
Original page
ABSTRACT
We presented data showing that the CART-19 cells expressing the 4-1BB signaling domain can have unprecedented and massive in-vivo expansion, traffic to tumor sites, persist long term in vivo, and induce rapid and potent anti-tumor activity in chemotherapy refractory CLL patients.
Journal: Journal of Cancer
ISSN 1837-9664
Volume: 2;
Issue: 1;
Start page: 331;
Date: 2011;
Original page
ABSTRACT
We presented data showing that the CART-19 cells expressing the 4-1BB signaling domain can have unprecedented and massive in-vivo expansion, traffic to tumor sites, persist long term in vivo, and induce rapid and potent anti-tumor activity in chemotherapy refractory CLL patients.
