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Chronic phenytoin therapy-induced vecuronium resistance

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Author(s): Chowdhury Lopamudra | Laha Arpita | Chaudhuri Tamonash | Chatterjee Suparna

Journal: Indian Journal of Pharmacology
ISSN 0253-7613

Volume: 43;
Issue: 2;
Start page: 214;
Date: 2011;
Original page

Keywords: Drug interaction | phenytoin | resistance | vecuronium

ABSTRACT
This case report highlights a clinically significant pharmacokinetic drug interaction between phenytoin, a widely used anticonvulsant and vecuronium, a non-depolarizing neuromuscular blocker which led to vecuronium resistance.
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