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Cicatrizing effect of Opuntia ficus-indica aqueous extract and seeds powder in New Zealand rabbits

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Author(s): Bouchra Souheila BEN LAKSIRA | S. HALMI | Z. DJERROU | K. BEROUAL | K. BACHTARZI | Z. MAAMRI | Y. HAMDI PACHA

Journal: International Journal of Medicinal and Aromatic Plants
ISSN 2249-4340

Volume: 3;
Issue: 2;
Start page: 159;
Date: 2013;
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Keywords: Burns | wound healing | Opuntia ficus-indica L. | rabbits

ABSTRACT
The present study aimed to evaluate the healing effect of Opuntia ficus-indica (L.) following experimental burns in the rabbit model. To do this, we have prepared two products from our plant material: a homogeneous aqueous extract from cladodes and a fine powder from the seeds of this plant. In a second step, we have shaved six New Zealand rabbits over the entire dorsal surface. Twenty-four hours later, four burns were made on the back of each rabbit, the treatments were performed in the following manner: Burn A was not treated (control), burning B was treated with aqueous extract, burning C was treated with Cicatrol® (as a healing reference drug), burning D was treated with a mixture of aqueous extract and seeds powder (v/v). The evolution of the healing process was investigated daily. The results have shown a significant reduction of healing times in the three treatment groups. No significant difference was observed between the aqueous extract and the reference drug. However, there was a significant difference between the mixture and all the other groups. Our study concludes that Opuntia ficus-indica L. may stimulate the cicatrizing process of experimental burns in the rabbits.
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