Academic Journals Database
Disseminating quality controlled scientific knowledge

Clinical manifestation of celiac disease diagnosed in children of 4 years and above in self-study --- Obraz kliniczny celiakii rozpoznanej po 4 roku zycia w materiale wlasnym Kliniki Alergologii, Gastroenterologii i Zywienia Dzieci Uniwersytetu Medycznego w Lodzi

ADD TO MY LIST
 
Author(s): Magdalena Kostrzewska | Ewa Toporowska-Kowalska | Joanna Kudzin | Krystyna Wssowska-Krolikowska

Journal: Przegląd Pediatryczny
ISSN 0137-723X

Volume: 37;
Issue: 2;
Start page: 237;
Date: 2007;
Original page

ABSTRACT
Background: Changing clinical manifestation of celiac disease could be the cause of diagnostic difficulties and recognition de- lay. The aim of the study is evaluation of clinical manifestation of celiac disease in children of 4 years and above in Children's Aler- gology, Gastrenterology and Nutrition Department of Medical University, Lods, in self-study in 2004-2006. Material and methods: Analysis of celiac clinical symptoms in a group of 17 children (11 girls/6 boys; average 11.12+/-4.67years), recognized >4 years old. Celiac disease was defined as classical (CK) and atypical (CA). Results: CK was found in 8 children (4 girls/4 boys; average 12.06+/-5.06years), CAin 9 (7 girls/2 boys; average 10.28+/-4.42 years). In the CK group 3 cases of full-symptom celiac disease were recognized (z-score BMI -0.89+/-0.07, anaemia, behavior disorders); in others (z-score BMI 0.24+/-0.39) diarrhoeas and abdominal pains were dominating. In anamnesis in children with CK anaemia resistant to treatment (n=3) and malabsorption (n=3) were found. In CA group in 6/9 children (z-score BMI -0.53+/-1.21) celiac disease diagnosis was preceded by other autoimmunologic disorders (juvenile chronic arthritis - JCA, type 1 diabetes mellitus - T1DM, T1DM and Graves-Basedov disease). Out of them in 2 patients height deficiency, in 3 recurrent abdominal pain and in 1 periodic diarrhea were observed. Three more children with undernutrition (z-score BMI -2.09+/-0.85, anaemia, trophical changes in oral cavity, enamel hypoplasia) and behavior disorders (2/3) were also classified into CA group despite their parents negation of gastrointestinal symptoms. Conclusion: 1. Clinical manifestation of celiac disease diagnosed in children 4 years and above could be variable and differentiation between latent and late-diagnosed form, sometimes difficult. 2. In children with autoimmunological disorders and positive serological screening into celiac disease, full diagnostics is needed, despite the lack of evident celiac disease symptoms.
Why do you need a reservation system?      Save time & money - Smart Internet Solutions