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Clinical Profile of Dengue Infection in Patients with Hematological Diseases

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Author(s): Sanjeev Kumar Sharma | Tulika Seth | Pravas Mishra | Nitin Gupta | Narendra Agrawal | Shobha Broor | Manoranjan Mahapatra | Renu Saxena

Journal: Mediterranean Journal of Hematology and Infectious Diseases
ISSN 2035-3006

Volume: 3;
Issue: 1;
Start page: e2011039;
Date: 2011;
Original page

Keywords: Hematological diseases | Dengue | Cytopenias

ABSTRACT
Managing hematological disorders in a tropical country presents several unique diagnostic and management problems. Apart from the disease process, we need to be aware of infections that can exacerbate or mimic serious hematological problems. We present here a series of five patients with pre-existing hematological diseases who were infected by dengue virus. These cases highlight the need to keep a strong suspicion of common endemic diseases in tropical countries before considering extensive workup for the basic hematological disease. There was no mortality and all patients recovered without any significant impact on their pre-existing hematological condition inspite of their low baseline blood counts. There was no excessive bleeding, prolonged stay in the hospital or relapse of underlying hematological disease in these patients and the only major concern was the increased anxiety among both the patient and treating physician regarding the relapse/progression of pre-existing hematological disease.

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