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A Clinical Study of a Cell-Based MAGE-A3 Active Immunotherapy in Advanced Melanoma Patients

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Author(s): Vincenzo Russo, Francesca Lunghi, Raffaella Fontana, Marco Bregni

Journal: Journal of Cancer
ISSN 1837-9664

Volume: 2;
Issue: 1;
Start page: 329;
Date: 2011;
Original page

ABSTRACT
In this bi-institutional study, twenty-three stage IIIC-IV MAGE-A3+ melanoma patients were vaccinated with M3TK-GML biweekly at three dose levels, with a subsequent phase of vaccinations at the maximum dose level. Anti-MAGE-A3 and anti-TK T cells were assessed by in vitro assay and delayed-type hypersensitivity skin testing.
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