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Clinicopatholological correlation of thyroid nodules

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Author(s): Shirish Chandanwale | Neha Singh | Harsh Kumar | Pagaro Pradhan | Charusheela Gore | Mohit Rajpal

Journal: International Journal of Pharmacy and Biomedical Sciences
ISSN 0976-5263

Volume: 03;
Issue: 03;
Start page: 97;
Date: 2012;
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Keywords: FNAC-Fine needle aspiration cytology | TFT-Thyroid function tests | USG-Ultrasonography | FN-Follicular neoplasm

ABSTRACT
The aim of the present study is to evaluate the accuracy of fine needle aspiration cytology (FNAC) in diagnosis of thyroid nodules in comparison with other diagnostic modalities and to make early and accurate differentiation of benign and malignant thyroid nodules with special focus on incidence of malignancy in thyroid nodules. FNAC was done in 150 patients who presented with thyroid nodules. Cytology findings were correlated with clinical and radiological diagnosis, Thyroid function tests (TFT) including serologic findings and Histology diagnosis. Incidence of malignancy in thyroid nodules was 6.75%. Sensitivity and specificity in our study was 90% and 100%, respectively with PPV, NPV and diagnostic accuracy of 100%, 90% and 87.5%, respectively. FNAC is a gold standard for preoperative assessment of thyroid nodules. Early and accurate diagnosis reduces surgical intervention, morbidity and mortality.
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