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Comparative analgesic effect of Ligusticum chuanxiong pieces and its products in mice

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Author(s): GAO Demin | XU Lingchuan

Journal: Pharmacognosy Magazine
ISSN 0973-1296

Volume: 6;
Issue: 22;
Start page: 132;
Date: 2010;
Original page

Keywords: Analgesic effect | chuanxiong | dysmenorrhea test | hot plate test | writhing test

ABSTRACT
The present study was undertaken with the objective of finding out the comparative analgesic effect of Ligusticum chuanxiong (LC) pieces decoction, LC formula granule decoction, liquored LC pieces decoction and liquored LC formula granule decoction. The analgesic effects were analyzed using the hot plate and acetic-induced writhing test in mice, and antidysmenorrheic effect was observed with primary dysmenorrhea model. The results showed that four kinds of LC decoction had definite effect in delaying incubation period and decreasing the writhing frequency within 30 min. They also effectively relieved dysmenorrhea. Moreover, liquored LC had better analgesic effect than crude LC in four decoctions.
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