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Comparative Analysis of Chlorhexidine Gluconate, Povidone Iodine and Chloroxylenol as Scrubbing Solution

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Author(s): A.S. Yakubu | A.A. Abubakar | M.D. Salihu | A. Jibril | I. Isah

Journal: British Journal of Pharmacology and Toxicology
ISSN 2044-2459

Volume: 1;
Issue: 2;
Start page: 93;
Date: 2010;
Original page

Keywords: Chlorhexidine gluconate | chloroxylenol | povidone iodine | red sokoto goat | scrubbing solution | surgical site

ABSTRACT
The study was carried out to determine the efficacy of stock concentration of the commonly used disinfectant as scrub solution for surgical site in goats. The evaluation of efficacy and safety of commercially available disinfectant and antiseptic (0.3% Chlorhexidine gluconate, 0.4% Chloroxylenol and 4% Povidone iodine) as scrub solution for surgical site, using stock concentration was assessed in thirty (30) Red Sokoto goats undergoing non elective surgical procedures at Usmanu Danfodiyo University, Veterinary Teaching Hospital and Zonal Veterinary Clinic, Sokoto. Colony counting was used to quantify skin bacteria Colony Forming Unit (CFU) at surgical site before and after skin preparation. Reduction of CFU before and after preparation was significant with all the three disinfectants compared (p
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