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Comparative investigation on the efficacy of tulathromycin and florfenicol in the treatment of bronchopneumonia in feedlot calves

Author(s): Jezdimirović Milanka | Aleksić Nevenka | Barać-Bašević Ana | Žutić Milenko | Ivetić Vojin | Radanović Oliver | Jezdimirović Nemanja

Journal: Veterinarski Glasnik
ISSN 0350-2457

Volume: 65;
Issue: 3-4;
Start page: 153;
Date: 2011;
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Keywords: tulathromycin | florfenicol | efficacy | BRD | Pasteurella multocida | calves

The clinical efficacy of tulathromycin (TU) and florfenicol (FL) in the treatment of bronchopneumonia (BP) caused by Pasteurella multocida which was isolated from nose swabs of diseased calves has been examined. The symptoms of bronchopneumonia (BP) were quantified by means of the clinical score (CS) with a maximum of 47 points. In the current investigation the average CS in diseased calves was 23.5± 0.15. The clinical efficacy of TU and FL was assessed every day in the first week after the administration of the drugs and was based on the decrease in CS and on microbiological findings on days 7, 28 and 35 after the completion of therapy. Tulathromycin was administered s.c., in the prescribed therapeutic dose (2.5 mg/kg BW), and florfenicol s.c., twice at a 48 h interval, in its respective therapeutic dose (40 mg/kg BW). In spite of the repeated administration of FL, TU was significantly more rapid to decrease the major clinical symptoms in the first four days following the application, in comparison with FL (P
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