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COMPARATIVE STUDIES ON POVIDONE-IODINE OINTMENT AND GEL

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Author(s): T. Mangilal*, K. S. K. Rao Patnaik , R. Sivakumar , Y. Sudhakar and S. K. Basu

Journal: International Journal of Pharmaceutical Sciences and Research
ISSN 0975-8232

Volume: 3;
Issue: 11;
Start page: 4507;
Date: 2012;
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Keywords: Antimicrobial activity | Gel | Ointment | Povidone-iodine | Wound healing

ABSTRACT
Povidone-Iodine Ointment was prepared using polyethylene glycol base by fusion method and the gel was prepared using Poloxamer 407 as a gelling agent by cold process. The different characteristics of povidone-iodine ointment and gel were compared from the results obtained for assay and total, available and complex iodine contents. These values were comparable with marketed formulations. The formulations were tested for wound healing and antimicrobial activity. Wound healing studies show that the time taken for complete wound healing was slightly less for prepared povidone-iodine ointment and gel than the marketed preparations. Antimicrobial activity also found to be almost equal for the different formulations.
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