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COMPARATIVE STUDIES OF SYNTHESIS, STABILITY AND ANTIBACTERIAL ACTIVITY OF ZINC OXIDE NANO-PARTICLES

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Author(s): Shailaja D, Shailaja M*, Roselin P, Manasa J and Shalini N

Journal: International Journal of Bioassays
ISSN 2278-778X

Volume: 2;
Issue: 6;
Start page: 914;
Date: 2013;

Keywords: Zinc oxide nano-particles | Antibacterial Activity | Agar Well Diffusion.

ABSTRACT
Research related to the antibacterial activity of nanoparticles will enable new developments in the field of nanomedicine. Targeted drug delivery, diagnostics, magnetic resonance, imaging etc., are possible because of the biological cell interactions of the nanoparticles. The present study focuses on one such interaction of ZnO nanoparticles. The antibacterial activity and stability of ZnO nanoparticles synthesised using different methods was investigated. The inhibitory effect of ZnO nanoparticles against Escherichia coli, Proteus vulgaris, Pseudomonas, Propionibacterium acnes, Bacillus, Klebsiella and Staphylococcus aureus was tested by agar well diffusion method. The zones of inhibition for all the selected bacterial strains were measured. The ZnO nanoparticles synthesised by the different methods were effective against all the organisms tested and the nanoparticles were quite stable.
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