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Comparative Study Of PUVASOL And Oral Corticosteroid Minipulse In The Treatment Of Vitiligo

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Author(s): Huda M.M | Saikia Prasanna Kumar

Journal: Indian Journal of Dermatology
ISSN 0019-5154

Volume: 47;
Issue: 4;
Start page: 214;
Date: 2002;
Original page

ABSTRACT
Fifty patients in each group with matched age, sex, duration of disease and possible extent of disease were evaluated for response to treatment with PUVASOL and oral minipulse after six months. Effects of both the treatment regimens. At the end of six months, 32 patients showed pigmentation, 12 showed no response and 6 deteriorated in those receiving PUVASOL, while 29 showed pigmentation, 17 showed no response and 4 continued to progress on therapy with oral minipulse. In both regimens, the rate and extent of improvement were unrelated to age, sex, duration and activity at presentation. Lesions on the face and neck responded maximally, while acral, mucosal, genital lesions and lesions with associated leucotrichia responded poorly to either regimen. Minor side effects were noted with both the therapeutic modalities. However, none were severe enough to discontinue therapy.
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