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Comparison of central corneal thickness measured by three optical measurement devices with ultrasound pachymetry

Author(s): Duo Peng | Qin-Mei Wang | Shi-Hao Chen

Journal: Guoji Yanke Zazhi
ISSN 1672-5123

Volume: 13;
Issue: 12;
Start page: 2545;
Date: 2013;
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Keywords: Visante OCT | SL-OCT | OrbscanⅡz | A-mode ultrasound pachymetry | central corneal thickness

AIM:To compare the difference and correlation of central corneal thickness(CCT)measured by Zeiss Visante Anterior Segment Optical Coherence Tomography(Visante OCT), Heidelberg Slit-Lamp Anterior Segment Optical Coherence Tomography(SL-OCT), OrbscanⅡz Computerized Topography(OrbscanⅡz )and A-mode ultrasound pachymetry.METHODS:Forty-three patients with myopia(86 eyes)were included. Sequential measurements of CCT was performed by the same operator with two different anterior segment OCT devices(VisanteTM, Carl Zeiss, Meditec and Heidelberg EngineeringTM), OrbscanⅡz Computerized Topography(Bausch and Lomb IncTM)and A-mode ultrasound pachymetry. The consistency of measurements was statistically analyzed by one-way ANOVA and LSD pair-wise comparisons. The differences were analyzed by Pearson correlation coefficients.RESULTS:The average CCT measured by Visante OCT, SL-OCT, OrbscanⅡz, and A-mode ultrasound pachymetry were(521.05±29.88)μm,(533.73±31.83)μm,(534.02±32.96)μm, and(540.60±31.11)μm, the 95% confidence interval were(514.57~527.54),(526.83~540.65),(533.85~547.35),(536.75~544.45). There was statistically significant difference of CCT between using of Visante OCT and SL-OCT(P=0.009). There was statistically significant difference of CCT using of Visante OCT and A-mode ultrasound pachymetry(P
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