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COMPARISON OF DEMINERALIZING EFFECT OF COMMERCIAL EDTA PREPARATIONS AT DIFFERENT TIME INTERVALS BASED ON MEASUREMENT OF THE AMOUNT OF PHOSPHORUS RELEASED FROM HYDROXYAPATITE

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Author(s): Shetty Aditya | Hegde Mithra N | Mathew Tony | Bhat Ganesh

Journal: International Research Journal of Pharmacy
ISSN 2230-8407

Volume: 4;
Issue: 9;
Start page: 128;
Date: 2013;
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Keywords: EDTA | RC-PREP | Glyde | hydoxyapatite | Phosphorus

ABSTRACT
The objective of this in-vitro study is to compare the de mineralizing effect of commercial EDTA in different concentrations and different time intervals with respect to the amount of phosphorus released from hydroxyapatite. 96 freshly extracted maxillary central incisor roots were randomly grouped 4 groups of 24 specimens each. The first group, the control group was treated with saline. The second group was treated with a commercial preparation of EDTA- RC PREP. The third group was treated with a commercial preparation of EDTA- Glyde and the fourth group was treated with a solution of 17 % EDTA. All the groups were treated with the respective formulations for time intervals one, three, ten and fifteen minutes each. The solutions obtained from each of the four groups were analyzed for phosphorus content using colorimetric analysis. Group II i.e. R C Prep showed the highest de mineralizing effect for 1, 3 and 10 minutes respectively. Group III i.e. Glyde showed the highest de mineralizing effect for 15minutes. Among the solutions containing EDTA, Group IV i.e. 17 % EDTA solution showed the least de mineralizing effect, despite the higher concentration. This is because of the additives present in commercially available chelating pastes.
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