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Comparison Of Effects Of Autotransfusion And Tranexamic Acid On Post Cardiopulmonary Bypass Bleeding

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Author(s): Mehr AeinA | Davoodi S | Madani Givi M

Journal: Tehran University Medical Journal
ISSN 1683-1764

Volume: 61;
Issue: 6;
Start page: 450;
Date: 2003;
Original page

Keywords: Autotransfusion | Postoperative bleeding

ABSTRACT
The aim of this study was to compare the effects of intraoperative autotransfusion and tranexamic acid on post-operative bleeding and need for allogeneic transfusion."nMaterials and Methods: In a prospective, randomized study, 200 patients undergoing CABG allocated into two groups:"n□ AT group = 100 patients received 1-2 units (300-450cc) autologous blood after"ntermination of CPB"nD TX group = 100 patients received tranexamic acid, 15mg/kg before the injection"nof heparin and 15mg/kg after protamin injection"nPostoperative bleeding, transfusions, complications, ICU stay and hospital stay were recorded."nResults: The postoperative bleeding was lower in TX group (600 ml) than in AT group (1100 ml) (P
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