Academic Journals Database
Disseminating quality controlled scientific knowledge

A Comparison of the Effects of Typical and Atypical Antipsychotics on Inducing Obsessive-Compulsive Symptoms in Patients with Schizophrenia

Author(s): Shima Mohseni | Azizeh Afkham Ebrahimi | Badry Daneshamouz

Journal: Iranian Journal of Psychiatry and Clinical Psychology
ISSN 1735-4315

Volume: 13;
Issue: 4;
Start page: 328;
Date: 2008;
Original page

Keywords: typical antipsychotics | atypical antipsychotics | obsessive-compulsive symptoms | schizophrenia

AbstractObjectives: The effects of typical and atypical antipsychotics on inducing obsessive-compulsive symptoms in patients with schizophrenia were compared in this study. Method: In a comparative-descriptive study 64 patients with schizophrenia (32 patients in typical antipsychotic group and 32 patients in atypical antipsychotic group) were investigated. All patients with a confirmed diagnosis of schizophrenia based on Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I), underwent Yale-Brown Obsessive Compulsive Scale (Y-BOCS) and Brief Psychiatric Rating Scale (BPRS) at the beginning, as well as three and six weeks after treatment. Data were analyzed using descriptive statistics, repeated measures analysis of variance, and t-test. Results: In the group receiving typical antipsychotics, mean Y-BOCS scores were 2.40, 2.30, and 2.18 at the beginning, at three weeks and at six weeks after treatment respectively. Also, in the group receiving atypical antipsychotics Y-BOCS scores were 4.12, 4.46, and 4.53 at the beginning, at three weeks and at six weeks after treatment respectively. The difference of Y-BOCS scores in the two groups receiving typical and atypical antipsychotics was close to significance before treatment, and significant at three and six weeks after treatment (p

Tango Jona
Tangokurs Rapperswil-Jona

     Affiliate Program