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Congenital cytomegalovirus infection. Is there a breakthrough?

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Author(s): Bar-Oz B | Berkovitch M | Ford-Jones L | Koren G

Journal: Canadian Family Physician
ISSN 0008-350X

Volume: 47;
Issue: 6;
Start page: 1179;
Date: 2001;
Original page

ABSTRACT
QUESTION: My 26-year-old patient is planning her first pregnancy in the coming month. She works in a day-care centre. Recently, two cases of cytomegalovirus (CMV) infection were diagnosed in her class. What tests should she have before and during the pregnancy, and how should I care for her? ANSWER: Cytomegalovirus infection, the most common congenital viral infection in humans, carries high risk of long-term morbidity and mortality. Seronegative mothers of children in day-care centres are at as high risk of acquiring the infection as day-care workers themselves. The immune status of at-risk patients should be evaluated as pregnancy progresses. Evidence of fetal infection does not necessarily mean fetal disease or damage. With a primary-infected fetus, termination of pregnancy might be discussed with the parents.
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