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COPPER (I) ASSISTED CATALYST DIMERISATION OF TERMINAL ALKYNES AND THEIR ANTIBACTERIAL STUDIES

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Author(s): D. Munirajasekhar | C. Paul raj | R. Lakshmipathy

Journal: International Journal of Research in Ayurveda and Pharmacy
ISSN 2229-3566

Volume: 2;
Issue: 1;
Start page: 325;
Date: 2011;
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Keywords: Cu (I) catalyst | Dimerisation | Terminal alkynes | 1 | 3-diyn-diols.

ABSTRACT
Terminal alkynes undergo oxidative-coupling smoothly in the presence of the Cu(I)Cl catalytic system. The reaction gives 1,3-diynes in excellent yields under mild conditions. Structures of the all synthesized compounds were established based on TLC, FT-IR, 1H NMR, and MASS spectral data. All the synthesized compounds were examined for antibacterial activity.
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