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Correlation of Post-Operative Hypoalbuminemia with Outcome of Pediatric Cardiac Surgery

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Author(s): Paridokht Nakhostin Davari | Avisa Tabib | Mehdi Ghaderian | Nozar Givtaj

Journal: Journal of Tehran University Heart Center
ISSN 1735-8620

Volume: 4;
Issue: 4;
Start page: 234;
Date: 2009;
Original page

Keywords: Congenital heart defect | Hypoalbuminemia | Cardiac surgical procedures

ABSTRACT
"nBackground: Hypoalbuminemia may be caused by liver disease, nephrotic syndrome, burns, protein-losing entropathy, malnutrition, and metabolic stress. Alterations in albumin in metabolic stress such as cardiac surgery have been previously investigated. We studied serum albumin concentration in children with congenital heart disease and also the association of hypoalbuminemia with mortality and morbidity after pediatric cardiac surgery. "nMethods: We measured serum albumin concentration prospectively in 300 children with congenital heart disease who underwent surgery between July and September 2008 in Shaheed Rajaee hospital. Serum albumin concentration was measured before and 48 hours after cardiac surgery and was subsequently compared between 2 groups: cyanotic and acyanotic and also with normal values. "nResults: Serum albumin concentration decreased on the second post-operative day in 70 (23.3%) patients. There was a positive correlation between the post-surgical hypoalbuminemia and cyanotic heart disease. The cyanotic children had lower serum albumin concentration than the acyanotic ones (P value

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