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Cortisol and pregnenolone as diagnostic criteria for evaluating the duration of dying of a person at the early stages of antemortem period

Author(s): Bilyakov A.M.

Journal: Морфологія
ISSN 1997-9665

Volume: 6;
Issue: 4;
Start page: 18;
Date: 2012;
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Keywords: pregnenolone | cholesterol | cortisol | trauma | steroidogenesis

The content of cortisol and its precoursor pregnenolone in adrenal tissue was evaluated with the purpose of determining the duration of dying of a human being influenced by a lethal traumatic factor. It is shown that pregnenolone as an intermediate component of steroidogenesis is not identified in adrenal tissue of the persons who died as a result of a traumatic factor influence. The amount of cortisol in adrenal tissue differs depending on the duration of dying of a person and can be used as a diagnostic criterion for evaluating the duration of dying of the person at an early stage of antemortem period.
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