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Cryosurgery (N2O) application to remove lip lesions of lipoid proteinosis syndrome: a case report

Author(s): Amir Mansour Shirani

Journal: Journal of Dental Research, Dental Clinics, Dental Prospects
ISSN 2008-210X

Volume: 2;
Issue: 2;
Start page: 68;
Date: 2008;
Original page

Lipoid proteinosis is a rare hereditary metabolic disorder transmitted as an autosomal recessive trait. It is characterized by the deposition of an amorphous hyaline-like material (glycoprotein) in the mucous membranes, skin and various internal organs. Cryosurgery (N2O) was applied to remove and reshape the lip lesions in a case of this rare syndrome. The patient was a 24-year-old female. Cryosurgery (−63ºC N2O for one minute) was performed to re-shape some areas of the upper lip. The lips were softer and had better esthetics after treatment. The use of cryosurgery offers advantages over surgery in reshaping of the lip lesions in this syndrome, since suturing is not feasible in rigid mucosa of these patients.
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