Academic Journals Database
Disseminating quality controlled scientific knowledge

Cure of alopecia areata after eradication of Helicobacter pylori: A new association?

ADD TO MY LIST
 
Author(s): Germán Campuzano-Maya

Journal: World Journal of Gastroenterology
ISSN 1007-9327

Volume: 17;
Issue: 26;
Start page: 3165;
Date: 2011;
Original page

Keywords: Alopecia areata | Helicobacter pylori | Molecular mimicry | Eradication treatment

ABSTRACT
Alopecia areata is a disease of the hair follicles, with strong evidence supporting autoimmune etiology. Alopecia areata is frequently associated with immune-mediated diseases with skin manifestations such as psoriasis and lichen planus, or without skin manifestations such as autoimmune thyroiditis and idiopathic thrombocytopenic purpura. Helicobacter pylori (H. pylori) infection is present in around 50% of the world’s population and has been associated with a variety of immune-mediated extra-digestive disorders including autoimmune thyroiditis, idiopathic thrombocytopenic purpura, and psoriasis. A case of a 43-year old man with an 8-mo history of alopecia areata of the scalp and beard is presented. The patient was being treated by a dermatologist and had psychiatric support, without any improvement. He had a history of dyspepsia and the urea breath test confirmed H. pylori infection. The patient went into remission from alopecia areata after H. pylori eradication. If such an association is confirmed by epidemiological studies designed for this purpose, new therapeutic options could be available for these patients, especially in areas where infection with H. pylori is highly prevalent.

Tango Jona
Tangokurs Rapperswil-Jona

     Save time & money - Smart Internet Solutions