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Cutaneous CD4+/ CD56 hematodermic neoplasm

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Author(s): Zindanci Ilkin | Kavala Mukaddes | Buyukbabani Nesimi | Kocaturk Emek | Koc Melek

Journal: Indian Journal of Dermatology, Venereology and Leprology
ISSN 0378-6323

Volume: 76;
Issue: 6;
Start page: 723;
Date: 2010;
Original page

Keywords: CD4+/CD56+ hematodermic neoplasm | blastic Natural killer cell lymphoma | natural killer lymphoma

ABSTRACT
CD4+/CD56+ hematodermic neoplasm, formerly known as blastic NK cell lymphoma, is a rare and aggressive neoplasm with a high incidence of cutaneous involvement, risk of leukemic dissemination and poor prognosis. The characteristic features are expression of the T helper inducer cell marker CD4 and the NK-cell marker CD56 in the absence of other T cell or NKcell specific markers. Because of the rarity of this disease, we describe a 48 year old woman suffering from CD4+/CD56+ hematodermic neoplasm on her cheek without leukemic infiltration.
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