Academic Journals Database
Disseminating quality controlled scientific knowledge

Cytogenetic study of women with premature ovarian failure

ADD TO MY LIST
 
Author(s): Pagni Denise | Melaragno Maria Isabel

Journal: Genetics and Molecular Biology
ISSN 1415-4757

Volume: 21;
Issue: 2;
Start page: 263;
Date: 1998;
Original page

ABSTRACT
Etiology of premature ovarian failure (POF) is unclear in most patients. Since some cases are related to X-chromosome abnormalities, cytogenetical studies were conducted in patients with POF. Lymphocyte cultures from eleven patients were compared to cultures from age-matched controls. All individuals presented normal karyotypes. Frequencies of aneuploid and structural chromosome aberrations did not differ between the groups. The X chromosome was more frequently involved in aneuploidy and in premature centromere division in both groups.
Why do you need a reservation system?      Affiliate Program