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Decreasing Systolic Blood Pressure Is Associated with Improving Estimated Glomerular Filtration Rate (eGFR) with Lifestyle Modification in Japanese Healthy Women

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Author(s): Miyatake,Nobuyuki | Shikata,Kenichi | Makino,Hirofumi | Numata,Takeyuki

Journal: Acta Medica Okayama
ISSN 0386-300X

Volume: 64;
Issue: 5;
Start page: 339;
Date: 2010;
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Keywords: systolic blood pressure | estimated glomerular filtration rate (eGFR) | metabolic syndrome | lifestyle modification

ABSTRACT
The link between changes in a subject's metabolic syndrome components and her estimated glomerular filtration rate (eGFR) was evaluated in healthy Japanese women. We used data for 53 Japanese women (46.0±10.9 years) with a 1-year follow up. eGFR was defined by a new equation developed for Japan. There were no significant relationships between eGFR and clinical parameters at baseline. Subjects were given advice for dietary and lifestyle improvement. At the 1-year follow up, eGFR was significantly increased. In addition, changes in eGFR were weakly correlated with systolic blood pressure(r=-0.306, p=0.0260). A decrease in systolic blood pressure may be associated with improving eGFR in Japanese women.
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