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Designing Safer and Greener Antibiotics

Author(s): Andrew Jordan | Nicholas Gathergood

Journal: Antibiotics
ISSN 2079-6382

Volume: 2;
Issue: 3;
Start page: 419;
Date: 2013;
Original page

Keywords: antibiotic | resistance | environment | ionic liquid | green chemistry | biodegradation | toxicity

Since the production of the first pharmaceutically active molecules at the beginning of the 1900s, drug molecules and their metabolites have been observed in the environment in significant concentrations. In this review, the persistence of antibiotics in the environment and their associated effects on ecosystems, bacterial resistance and health effects will be examined. Solutions to these problems will also be discussed, including the pharmaceutical industries input, green chemistry, computer modeling and representative ionic liquid research.
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