Author(s): Takashi Naohara | Hiromichi Aono | Tsunehiro Maehara | Hideyuki Hirazawa | Shinya Matsutomo | Yuji Watanabe
Journal: Journal of Functional Biomaterials
ISSN 2079-4983
Volume: 3;
Issue: 1;
Start page: 163;
Date: 2012;
Original page
Keywords: cancer therapy | ablation treatment | high-frequency induction heating | AC magnetic field | shape magnetic anisotropy | magnetic flux direction | biocompatibility
ABSTRACT
To develop a novel ablation therapy for human solid cancer, the heating properties of a ferromagnetic carbon steel rod and a prototype Ti-coated needle using this carbon steel rod, were investigated in several high-frequency outputs at 300 kHz. In the former, the heating property was drastically different among the three inclination angles (θ = 0°, 45° and 90°) relative to the magnetic flux direction as a result of the shape magnetic anisotropy. However, the effect of the inclination angles was completely eliminated in the latter. It is considered that the complete non-oriented heating property relative to the magnetic flux direction allows the precise control of the ablation temperature during minimally invasive thermotherapy without a lead-wire connected to a fiber-optic thermometer. This newly designed Ti-coated device will be suitable for clinical use combined with its superior biocompatibility for ablation treatments using high-frequency induction heating.
Journal: Journal of Functional Biomaterials
ISSN 2079-4983
Volume: 3;
Issue: 1;
Start page: 163;
Date: 2012;
Original page
Keywords: cancer therapy | ablation treatment | high-frequency induction heating | AC magnetic field | shape magnetic anisotropy | magnetic flux direction | biocompatibility
ABSTRACT
To develop a novel ablation therapy for human solid cancer, the heating properties of a ferromagnetic carbon steel rod and a prototype Ti-coated needle using this carbon steel rod, were investigated in several high-frequency outputs at 300 kHz. In the former, the heating property was drastically different among the three inclination angles (θ = 0°, 45° and 90°) relative to the magnetic flux direction as a result of the shape magnetic anisotropy. However, the effect of the inclination angles was completely eliminated in the latter. It is considered that the complete non-oriented heating property relative to the magnetic flux direction allows the precise control of the ablation temperature during minimally invasive thermotherapy without a lead-wire connected to a fiber-optic thermometer. This newly designed Ti-coated device will be suitable for clinical use combined with its superior biocompatibility for ablation treatments using high-frequency induction heating.
