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Diagnostic dilemma in a child with congenital heart disease on sildenafil

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Author(s): Zaki Syed | Dadge Deepak | Asif Shujaath | Shanbag Preeti

Journal: Indian Journal of Pharmacology
ISSN 0253-7613

Volume: 41;
Issue: 3;
Start page: 148;
Date: 2009;
Original page

Keywords: Adverse effects | congenital heart disease | pulmonary hypertension | sildenafil

ABSTRACT
Sildenafil is used in infants and children mainly for the treatment of pulmonary hypertension associated with congenital heart disease. Some side-effects of sildenafil are similar to the symptoms and signs of congestive heart failure in children. We present a case of a two-month-old infant with supracardiac total anomalous venous connection and pulmonary hypertension, who presented with severe sweating and tachycardia after institution of sildenafil therapy. He improved dramatically on discontinuation of the drug.
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