Academic Journals Database
Disseminating quality controlled scientific knowledge

Differential diagnosis of acute abdominal pain – acute intermittent porphyria

Author(s): Mislav Klobučić | Duška Šklebar | Renata Ivanac | Dragica Vrabec Matković | Anita Jug-Klobučić | Ivan Šklebar

Journal: Medicinski Glasnik
ISSN 1840-0132

Volume: 8;
Issue: 2;
Start page: 298;
Date: 2011;
VIEW PDF   PDF DOWNLOAD PDF   Download PDF Original page

Keywords: intermittent porphyria | autosomal disorder | abdominal pain

Acute intermittent porphyria (AIP) is a rare autosomal dominant disorder of heme biosynthesis in liver due to deficiency of porphobilinogen deaminase enzyme. Clinically, AIP is dominatedby a colicky type pain, which does not subside after taking usual analgesics. Additional frequent symptoms are vomiting, hypertension, peripheral neuropathy, seizures, depression, delirium and coma. This paper reported a case of a twenty-fi- ve-year-old female patient, who had undergone a period of six days between the first presentationto the medical department and the diagnosis confirmation. It has accentuated possible mistakes in symptomatic therapy administration as well as dangers of a delayed diagnosis.
Why do you need a reservation system?      Affiliate Program