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DIURETIC ACTIVITY OF LEAVES OF BALANITES ROXBURGHII LINN.

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Author(s): Nitin S. Wani

Journal: International Journal of Pharmaceutical Research and Development
ISSN 0974-9446

Volume: 2;
Issue: 4;
Start page: 14;
Date: 2010;
Original page

Keywords: Balanites Roxburghii | Diuretic | Ethanol and methanol extract

ABSTRACT
Balanites roxburghii is a spiny, evergreen tree. It is common in open sandy plains of the Indian peninsula, western Rajastan, west Bengal, Maharashtra and drier parts of India. The dried leaves of Balanites Roxburghii Linn. were subjected to successive extraction using the solvents ethanol and methanol. The prepared extracts were then subjected to preliminary phytochemical screening. It was found that the plant possesses alkaloids, glycosides, saponins, flavones and phenolic compounds. The diuretic effect was examined by treating different groups of wistar albino rats with (150 and 300mg/kg) oral doses of ethanol and methanol extracts. The volumes of urine, urinary concentration of sodium and potassium ions were the parameters of the study. Frusemide was used as standard. The results indicate that ethanol and methanol extract at 300 mg/kg body weight shows a significant (p
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