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Diversity Oriented Design of Various Benzophenone Derivatives and Their in Vitro Antifungal and Antibacterial Activities

Author(s): Li Sun | Jie Wu | Min Luo | Xiaoli Wang | Man Pan | Zhaopin Gou | Dequn Sun

Journal: Molecules
ISSN 1420-3049

Volume: 16;
Issue: 11;
Start page: 9739;
Date: 2011;
Original page

Keywords: benzophenone derivatives | bioactivity | phytopathogenic fungi | vibrio

A series of new substituted benzophenone derivatives was designed, synthesized and screened for their antifungal and antibacterial activities. The bioassays indicated that most of the synthesized compounds showed some antifungal activity against the tested phytopathogenic fungi, but lower antibacterial activities towards the five vibrios isolated from marine sources. The preliminary structure activity relationship (SAR) of the compounds was also discussed.

Tango Jona
Tangokurs Rapperswil-Jona

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