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Effect of Aqueous Extract of Leaf of Aegle Marmelos on Testicular Activities in Rats

Author(s): Uttam Kumar Das | Rajkumar Maiti | Debasis Jana | Debidas Ghosh

Journal: Iranian Journal of Pharmacology and Therapeutics
ISSN 1735-2657

Volume: 5;
Issue: 1;
Start page: 21;
Date: 2006;
Original page

Keywords: Aegle marmelos | Steroidogenic key enzymes | Plasma testosterone | Germ cells

The aqueous extract of leaf of Aegle marmelos (Bael) at the dose 50 mg/100 g body weight resulted a significant diminution in the activities of testicular key steroidogenic enzymes along with low levels of plasma testosterone and relative wet weights of sex organs in respect to control without any significant alteration in general body growth. Germ cells numbers in different generation at stage VII of seminiferous epithelial cell cycle were diminished significantly after the treatment of the above extract. The above mentioned dose did not exhibit any toxicity in liver and kidney. Therefore, it may be predicted that the aqueous extract of leaf of Aegle marmelos has a potent antitesticular effect at a specific dose.
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