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The Effect of Aqueous Extract of the Leaves of Eucalyptus Globules on the Blood Glucose Level in Fasted Rats

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Author(s): Shahbaa Muslem Ismail

Journal: Iranian Journal of Pharmacology and Therapeutics
ISSN 1735-2657

Volume: 6;
Issue: 2;
Start page: 239;
Date: 2007;
Original page

Keywords: Eucalyptus globules | Antihyperglycemic plant | Ddiabetes mellitus

ABSTRACT
The aim of this study is to determine the effect of the aqueous extract of the leaves of Eucalyptus globules on blood glucose level in fasted rats, and to find a new medical adjunct to anti-diabetes drugs. The aqueous extract of Eucalyptus was administered in various doses (150-400 mg/kg) orally. Blood glucose level was checked 2-6 h after treatment. The study showed that oral administration of the extract (250 mg/ kg ) resulted in significant decrease in blood glucose level peaking at 4 hours, in a dose-dependent manner (p< 0.0005 ). This effect declines after 6 hours of feeding in all the doses examined ( 150 , 250 , 400 mg/kg body weight ).These data indicates that Eucalypyus globules represents an effective antihyperglycaemic adjunct for the treatment of diabetes and a potential source for the discovery of new orally-active agent in future.

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