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Effect of aqueous extract of Syzygium cumini Pulp on antioxidant defense system in streptozotocin induced diabetic rats

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Author(s): Namasivayam Rekha | Ramachandran Balaji | Munuswamy Deecaraman

Journal: Iranian Journal of Pharmacology and Therapeutics
ISSN 1735-2657

Volume: 7;
Issue: 2;
Start page: 137;
Date: 2008;
Original page

Keywords: Free Radical | Syzygium Cumini | Diabetic Rats

ABSTRACT
The aqueous extract of Syzygium cumini (Pulp) was investigated for its possible hypoglycemic and antioxidant potentials in streptozotocin (STZ) induced diabetic wistar female rats. A single intraperitoneal injection of STZ at a dose of 55 mg/kg body weight elevated the glucose levels more than 230 mg/dl after 3 days. Treatment with the aqueous extract of Syzygium cumini (Pulp) at 100 mg/kg and 200 mg/kg body weight resulted in significant reduction (p
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