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The Effect of Hydro Alcoholic Nettle (Urtica dioica) Extract on Oxidative Stress in Patients with Type 2 Diabetes: A Randomized Double-blind Clinical Trial

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Author(s): N. Namazi | A. Tarighat | A. Bahrami

Journal: Pakistan Journal of Biological Sciences
ISSN 1028-8880

Volume: 15;
Issue: 2;
Start page: 98;
Date: 2012;
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Keywords: antioxidant | complications | type 2 diabetes | free radical | Nettle

ABSTRACT
Diabetes type 2 is a metabolic disorder that characterized by hyperglycemia and insulin resistance. Hyperglycemia and impairment of oxidant/antioxidant balance, can increase oxidative stress and increase risk of cardiovascular disease. In the present study, Effects of hydro alcoholic extract of Nettle on oxidative stress in type 2 diabetes were evaluated. Fifty patients (27 men, 23 women) with type 2 diabetes patients were studied. They received 100 mg kg-1 of nettle extract of body weight hydro alcoholic for 8 weeks. At the baseline and end of 8th weeks of intervention blood levels of oxidative stress markers were measured. Data was analyzed by SPSS version 18, p
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