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EFFECT OF PETROLEUM ETHER EXTRACT OF MALKANGNI (CELESTROUS PENICULATUS WILD) ON OPEN FIELD BEHAVIOR IN SWISS ALBINO MICE

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Author(s): Feroz Ahmad Wani | Arsheed Iqbal | Jafri M.A | Afroza Jan | Khalid Ghazanfar Mustafa

Journal: International Research Journal of Pharmacy
ISSN 2230-8407

Volume: 4;
Issue: 8;
Start page: 145;
Date: 2013;
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Keywords: Celastrus paniculatus wild | grooming | rearing | Imipramine | open field behavior.

ABSTRACT
The effects of an acute and repeated administration of petroleum ether extract from the seeds of Malkangani (Celestrus Paniculatus Wild) on explorarity activity and emotional reactivity was examined on open field behaviour in Swiss albino mice. A single acute administration of the extract did not induce any significant behavioral effect. However repeated administration of the test drug significantly increased grooming, rearing and decreased defecation in dose related manner.
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