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Effect of Vitamin C Supplementation on Oxidative Stress Markers Following Thirty Minutes Moderate Intensity Exercise in Healthy Young Women

Author(s): M. Karandish | S.T. Rahideh | A.Z. Moghaddam

Journal: Journal of Biological Sciences
ISSN 1727-3048

Volume: 8;
Issue: 8;
Start page: 1333;
Date: 2008;
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Keywords: Vitamin C | malondialdehyde | glutathione

The aim of this double blind randomized controlled trial was to determine the effect of Vitamin C supplementation on oxidative stress following 30 min moderate intensity exercise. Forty-nine healthy young women randomly assigned into 500 mg day-1 vitamin C supplement (n = 25) or placebo (n = 24) groups for two weeks. Before supplementation and on the day after the intervention period, fasting blood samples were taken. Then all participants ran (1.4-1.7 m sec-1) for 30 min. Third blood samples were taken at the end of exercise. Plasma malondialdehyde (MDA) and vitamin C were measured using HPLC method. Plasma total glutathione was measured with ELISA method. No significant differences were observed in demographic and vitamin C intakes before intervention between groups. Plasma MDA levels decreased and plasma total glutathione increased significantly (p
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