Academic Journals Database
Disseminating quality controlled scientific knowledge

Effects of L-Cystine and L-Theanine Supplementation on the Common Cold: A Randomized, Double-Blind, and Placebo-Controlled Trial

ADD TO MY LIST
 
Author(s): Shigekazu Kurihara | Takenori Hiraoka | Masahisa Akutsu | Eiji Sukegawa | Makoto Bannai | Susumu Shibahara

Journal: Journal of Amino Acids
ISSN 2090-0112

Volume: 2010;
Date: 2010;
Original page

ABSTRACT
The common cold is one of the most frequent illnesses caused by viral infection. Recently, we have reported that oral administration of cystine and theanine (CT) to mice enhanced the humoral immune response associated with antibody production. Based on this mouse study, we investigated the effects of CT supplementation on the common cold in humans as a pilot study. A total of 176 healthy male volunteers were randomized to receive either placebo or CT (490 mg) tablets twice daily for 35 days. The incidence outcome was assessed using the definition in our laboratory based on questionnaires regarding cold symptoms. The incidence of subjects with colds during the trial was significantly lower in the CT group than in the placebo group, although the duration of the colds was not significantly different between the groups. These results suggest that CT supplementation may be useful for the prevention of the common cold.
Why do you need a reservation system?      Save time & money - Smart Internet Solutions