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The effects of topical application of sunflower-seed oil on open wound healing in lambs

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Author(s): Marques Silvio Romero | Peixoto Christina A. | Messias Júlio Brando | Albuquerque Alessandra Ribeiro de | Silva Junior Valdemiro Amaro da

Journal: Acta Cirurgica Brasileira
ISSN 0102-8650

Volume: 19;
Issue: 3;
Date: 2004;
Original page

Keywords: Sunflower-seed oil | Topic use | Wound healing

ABSTRACT
PURPOSE: To demonstrate the effects of the use of sunflower seed oil on the treatment of skin wounds. METHODS: Eighteen male Saint Inês lambs were divided in 3 groups according to the pos-operative (7, 14 and 21 days). After antisepsis and local anestesia, two 4cm² wounds on each side of the thoracic region, close to the scapule were surgically produced. The experimental wounds were treated with sunflower seed oil, with high concentration of linoleic acid (LA), and the control ones with sterilized Vaseline. Biopsies of the pos-operative wounds tissue were performed on the 7th, 14th, 21st days and histologically evaluated. RESULTS: Topic application of sunflower seed oil accelerated healing process at the 7th and 21st days, reducing wound area and increasing wound contraction. Granulation tissue increased faster on treated wounds. The epidermis of the treated wounds was completely recovered when compared to control wounds. CONCLUSION: The topic use of sunflower seed oil accelerated the healing process, and it can be used as an alternative therapy on second intention wound healing.
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