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Effects of weight reduction on the enzymatic antioxidants and its association with dietary intakes of copper, zinc, iron, selenium and magnesium in obese women

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Author(s): SA Keshavarz | M Ramezanipour | M Jalali | MR Eshraghian | H Sadrzade Yeganeh

Journal: Journal of School of Public Health and Institute of Public Health Research
ISSN 1735-7586

Volume: 6;
Issue: 2;
Start page: 1;
Date: 2008;
Original page

Keywords: Obesity | Enzymatic antioxidants | Weight loss | Trace elements | Women

ABSTRACT
Background and Aim: Body mass index (BMI) is a generally accepted indicator of body weight and obesity. A BMI>30 indicates obesity, which is regarded as a risk factor for many diseases, because their pathogeneses are associated with increasing numbers of free radicals derived from oxygen. The present study was a clinical trial carried out in order to study the effects of weight loss on enzymatic antioxidants and its association with dietary intakes of copper, zinc, iron, selenium and, magnesium in obese women."nMaterials and Methods: Thirty obese women, 19-50 years old, of whom informed consent was obtained, were included in the study. Information was collected on their general characteristics, and anthropometric measurements were made. A diet with a 500- to 1000-calorie deficit was recommended to the subjects, on the basis of micronutrient intakes estimated through a 24-hour dietary recall questionnaire 3 days before and after the intervention. The aim was to bring about a weight loss of 10%. A 10-ml blood sample was taken from each subject, before and after intervention, for enzymatic measurement of enzymatic antioxidants in the red blood cells. "nResults: Weight loss caused a significant increase (p

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